抗生素 破壞腸道免疫力Antibiotics destroy intestinal immunity

抗生素 破壞腸道免疫力 【新華網】美國研究人員在英國「自然」周刊上發表的1篇文章中指出，使用抗生素有可能破壞腸道先天免疫力，這也是引起耐抗生素細菌感染的原因。 埃里克‧帕爾默領導的紐約「斯隆－凱特林癌症研究所」研究人員對耐抗生素細菌感染原因進行了研究。這是1種廣泛使用抗生素導致的並發症，將使患者的身體健康受到更大傷害。 研究發現，儘管抗生素能消滅腸道中的很多細菌，但由抗生素治療引起的腸道先天免疫功能損傷也為耐抗生素細菌繁殖提供了溫床。 研究人員在觀察實驗鼠接受抗生素治療後的反應時，在其體內發現了少量能夠抵抗微生物的腸蛋白RegⅢ伽馬。這種腸蛋白能夠消滅耐萬古霉素腸球菌等高耐抗生素細菌。 據此，科學家主張研發能夠提高腸內RegⅢ伽馬蛋白含量的療法，以避免因使用抗生素而導致的細菌感染。 2008-09-17 Antibiotics destroy intestinal immunity 【Xinhua U.S. researchers in the UK "Nature" magazine published an article that the use of antibiotics may undermine the intestinal innate immunity, which is caused by antibiotic-resistant bacterial infections. ‧ Eric Palmer led New York, "Sloan - Kettering Cancer Institute," researchers of antibiotic-resistant bacterial infection of the reasons were studied. This is the 1 kind of widespread use of antibiotics lead to complications, the health of the patients will be hurt more. The study found that although antibiotics to the eradication of many intestinal bacteria, antibiotics, but by the innate immune caused by intestinal dysfunction for antibiotic-resistant bacteria has provided a breeding ground. The researchers observed in the mice after antibiotic treatment response, his body found in a small amount of resistance to the intestinal microbial protein gamma Reg Ⅲ. This intestinal protein to the eradication of vancomycin-resistant enterococci such as antibiotic-resistant bacteria. Accordingly, the scientists advocate research and development to improve the intestinal Reg Ⅲ gamma protein content of the therapy in order to avoid the use of antibiotics caused by bacterial infection. 2008-09-17 View more information, see the World Journal reported that e-ePaper

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