破骨細胞>成骨細胞 就會骨鬆Osteoclasts> osteoblasts will be bone-song

破骨細胞>成骨細胞 就會骨鬆 【陳惠惠】人的骨頭終其一生都在汰舊換新，這樣的工作，靠的是「成骨」、「破骨」兩種細胞通力合作，一旦失衡，破骨細胞的活性大於成骨細胞時，就會導致骨頭中的鈣流失，就是所謂「骨質疏鬆」。 台北振興醫院骨科主治醫師曾國峰說，隨著老化，成骨細胞的數量、活性都會跟著下降，骨骼的外部堅硬緻密的「皮質骨」會由厚變薄，內部的「海綿骨」空隙也會增多。 台灣馬偕醫院骨科主治醫師張定國說，停經後婦女缺乏女性荷爾蒙，少了動情激素刺激，成骨細胞活性下降，連帶影響對破骨細胞的調控，加速骨質流失速度。男性雖也有更年期困擾，但骨質疏鬆情況不如女性嚴重。 雖然成骨細胞負責造骨，少了破骨細胞，還是無法汰舊換新。曾國峰說，成骨細胞一方獨大，破骨細胞失靈，無法吸附老舊、壞掉的骨頭時，骨頭會變得硬而脆，「一旦碰到外力，就像磁器受到撞擊，應聲碎裂」。 俗稱「大理石寶寶」的骨質石化症，就是極端之例，X光片中骨頭常呈全白影像，醫師說，嚴重的骨質疏鬆症患者，因為長期、高劑量使用破骨抑制劑，也有骨頭壞死的風險。 2008-11-02 Osteoclasts> osteoblasts will be bone-song Chen Huihui】 【human bones in their lives replacement, so that the work on the "osteoblasts" and "bone-breaking," the two cells together, once out of balance, Activity of osteoclasts is greater than osteoblasts Cells, it will lead to the loss of calcium in the bones, the so-called "osteoporosis." Taipei Hospital attending physician to revive the country have said that the peak, with the aging, the number of osteoblasts, the activity will follow the decline in bone density of the external hard "cortical" by thinning thick, in-house as a "sponge bone" The gap will increase. Taiwan's Mackay Memorial Hospital orthopedic physician Zhang Ting-kuo, said that the lack of post-menopausal women, estrogen, the less estrogen to stimulate, decrease the activity of osteoblasts, the spill-over effects on the regulation of osteoclasts, to accelerate the rate of bone loss. Although men are also troubled by menopause, osteoporosis, but the situation of women as serious. Although the osteoblasts responsible for building bone, short of osteoclasts, or can not be eliminated over a new leaf. Zeng Feng said that the osteoblasts dominance of one party, the failure of osteoclasts, the absorption can not be old, broken bones, the bones become brittle and hard, "once the forces encountered, as demagnetizer by the impact, answered broken Crack. " Known as the "marble baby," the petrochemical bone disease, is the extreme of cases, X-ray film bone Chang Cheng-wide white images, physicians say, serious osteoporosis patients because the long-term, high-dose use of inhibitors of bone-breaking as well as bone necrosis Risks. 2008-11-02 View more information, see the World Journal reported that e-ePaper

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