●胰島素是一種蛋白質,若以口服方式,在胃部消化時就會被胃酸破壞;因此,將藥劑直接注射至體內,可避開胃酸破壞,是唯一的給藥途徑。唯針刺的感覺並不好過,即使現在已有很多發明,大幅減少針刺痛感,不過,許多病患對針劑注射還是會卻步,因此,如何找到可以減少糖尿病患針刺苦痛的良方,便成為醫藥專家努力的目標。
皮下給藥 減少針刺的不適感
另外,目前發展出來自動輸注的胰島素幫浦,直接埋在患者皮下給藥,可減少針刺的不適感。台灣彰化基督教醫院新陳代謝科醫師林世鐸指出,這種給藥幫浦就像呼叫器大小,內部可裝胰島素的儲藥針筒,以小型電池驅動幫浦,利用精密的電腦晶片操控,自動精確地釋放微量胰島素,或由使用者操作而釋放,將注射軟管輸液套置入皮下,唯要注意的是,這輸液套管子約每2到3天更換一次。
使用方式 要聽醫護團隊指示
林世鐸指出,有些病患擔心使用幫浦會有發炎的危險,其實很高比率是因為消毒不完全,或拖到六、七天以上才更換輸液軟管所致。一般而言,使用病患需在醫護團隊的指導下充分了解步驟與使用方式,並如實地定期更換軟管,發炎的機率幾手微乎其微。
由於使用機器還需學習如何換算血糖等操作,因此,病患平均可在一周左右熟悉機器的操作,三個月內可以完全熟練。
林世鐸說,注射幫浦全日穩定供藥功能最適合胰島素分泌不穩定的病患,如低血糖症狀劇烈者,早晨肝醣製造增加,有「黎明現象」的病患,或日常生活與工作行程常會變動或不定,以致注射胰島素很不方便或常會忘記者,可以穩定供藥的幫浦是可以考慮的選擇。
不過林世鐸也提醒,若是病患連估算血糖都懶得做、或本身沒有測血糖能力者,他並不鼓勵這類患者使用這種幫浦;而孕婦因血糖高低會影響胎兒的發育,使用機器也要密切留意血糖值。
(本報綜合報導)
2008-11-16
Insulin pump fitted to a more regular blood sugar testing
● insulin is a protein, oral terms of the way, when digested in the stomach acid will be destroyed; As a result, the pharmaceutical direct injection to the body, can avoid the destruction of gastric acid, is the only route of administration. Acupuncture is not only feeling better, even if there is a lot of inventions, acupuncture reduced pain, but many of the patients will be deterred or injection, how to find acupuncture can reduce the pain of suffering from diabetes good, it Efforts to become a medical expert.
Subcutaneous administration of acupuncture to reduce the discomfort
In addition, the current developed automatic insulin infusion pump, directly buried in the patients with subcutaneous administration, acupuncture can reduce the discomfort. Taiwan Changhua Christian Hospital Physicians metabolic priest Lin pointed out that such a drug delivery pump as the size of pagers, can be fitted within the reservoir of insulin drug needles, small battery-powered pump, the use of sophisticated computer chips control, automatic release of accurate Trace insulin, or by the user and the release will be injected into the skin tube infusion sets, but it should be noted that this fluid-casing about every 2-3 days to replace one.
Use the health care team to listen to instructions
Lin pointed out that Murdoch, and some worry that patients using the pump would be the risk of infection, in fact, a very high rate because of incomplete sterilization, or until six or seven days or more before replacement hose caused by transfusion. In general, patients need to use the health care team under the guidance of the steps to fully understand and use, and faithfully replacement hoses on a regular basis, the rate of inflammation unlikely hands of a few.
Due to the use of machines need to learn how to convert sugar, and other operations, the average patient in a week or so familiar with the operation of the machine, can be fully proficient within three months.
Lin said that the duo, 24-injection pump for the stability of the drug most suitable for patients with unstable insulin secretion, such as severe hypoglycemia symptoms, manufacturing glycogen in the morning, "Dawn phenomenon" of patients, and in their personal lives and work of the regular tour Change or uncertainty, resulting in insulin injection is not easy or often forget, can be stabilized for the drug pump which could be considered for selection.
But the duo Lin also warns that even if patients are too lazy to do blood sugar estimates, or they do not have any ability to measure blood sugar, he does not encourage patients to use this type of pump; pregnant women and as a result of high or low blood sugar may affect fetal development, the use of machines also To closely monitor the blood sugar level.
(This roundup)
2008-11-16
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